Majd Machour 2023-2024

Institution of PhD:
Technion – Israel Institute of Technology
Academic Discipline of PhD:
Faculty of Biomedical Engineering
PhD Advisor/s:
Prof. Shulamit Levenberg, Faculty of Biomedical Engineering, Technion – Israel Institute of Technology
Dissertation Topic:
3D Bioprinting of Complex Multi-layered Tissue

Majd, born and raised in Nazareth, graduated summa cum laude from the Technion in 2019 with a double BSc in biomedical engineering and medical sciences. He was accepted into the MD/PhD program and started his MSc studies at the Technion’s faculty of biomedical engineering under the supervision of Prof. Shulamit Levenberg, in the field of tissue engineering and bioprinting.

Majd is working on developing complex, multi-layered vascularized tissue substitutes to treat severe defects. He is using 3D bioprinting, a promising technique, to fabricate these substitutes. However, there are still challenges to overcome before it can be used in clinical practice. One challenge is the non-uniform shrinkage of printed constructs during the post-printing tissue maturation, which can lead to variable engineered constructs with unpredictable size and shape. To overcome this problem, Majd has invented and developed a novel technology called “Print and Grow” that enhances the long-term structural stability of the printed objects. This technology allows for the fabrication of patient-specific geometries that can maintain their structural fidelity and cellular viability after long-term incubation.

Majd is also working on other challenges in tissue engineering, such as developing microsurgical techniques for the direct anastomoses of engineered blood vessels upon implantation, and researching and inventing new printable materials to allow for the fabrication of vascularized bone substitutes. These innovations and developments are crucial steps toward reaching the goal of fully engineered bioprinted tissue replacements.