Yael Korem 2016-2017
- Institution of PhD:
- Weizmann Institute of Science
- Academic Discipline of PhD:
- Molecular Biology
- PhD Advisor/s:
- Prof. Uri Alon
- Dissertation Topic:
- Optimal Division of Labor in Cells and Tissues
- Institution of Postdoc:
- Yale University
- Present Institution:
- Yale University
- Present Academic Position:
- Postdoctoral Fellow
Yael, a resident of Bet Lehem Ha’glilit in northern Israel sought simple, elegant mathematical tools in high school to describe and understand complex systems. This led her to the Hebrew University of Jerusalem, where she completed her BSc in physics in the Amirim interdisciplinary honors program for outstanding students. Realizing that the advent of new technologies calls for quantitative approaches to the most fascinating, fundamental questions, her MSc studies in mathematics and computer science at the Weizmann Institute of Science focused on bioinformatics. With her advisor, Prof. Uri Alon, she offered a framework for understanding high dimensional single-cell gene expression data by applying a theory of multi-objective systems, and demonstrated how this framework can be useful in analyzing data from various organisms and tissues. She presented her work at an international conference and published in Plos Computational Biology; the paper was later selected as the editor’s choice in Science magazine. In cooperation with Dr. Oded Rechavi’s lab at Tel Aviv University, Yael modeled the epigenetic inheritance mechanism of C. Elegance; this study appeared in Cell.
Today, she continues her PhD studies in Prof. Alon’s lab, seeking general design principles in biology. She is working on modeling various strategies for task allocation between cells in a tissue, seeking to discover the guiding principles behind strategy selection. In addition, she is using dynamic systems tools to model resource allocation for cellular tasks in E. coli.
Hoping to make science more accessible to the public, Yael served as a guide at the Bloomfield Science Museum in Jerusalem and volunteered in a school in Lod. She currently teaches bioinformatics and writes articles on popular science for the Weizmann Institute educational website, Davidson On-line.